Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a typical 2-4 losing team. They boast o

Meanwhile, the Texans haven't been as fortunate to begin the 2025 campaign. Houston has started 2-4 and is fresh off a 27-19 loss at the hands of the Seattle Seahawks. To make matters worse, the Texans could be without star wide receiver Nico Collins, who suffered a concussion against the Seahawks.

Those who were declared out Sunday were quarterback Brock Purdy (toe), center Jake Brendel (hamstring), edge rusher Bryce Huff (hamstring), wide receiver Ricky Pearsall Jr. (knee) and defensive lineman Yetur Gross-Matos (knee). Lenoir was questionable along with linebacker Luke Gifford (hamstring) as was guard/tackle Spencer Burford (knee).

The Houston Texans will be without Nico Collins for Sunday's game against the San Francisco 49ers. Jayden Higgins and Jaylin Noel must step up.

Ever since Kyle Shanahan took over as the head coach of the San Francisco 49ers, there has been a certain section of fans who have waited for the other shoe to drop.

The San Francisco 49ers need a linebacker and it just so happens their old friend, Houston Texans head coach DeMeco Ryans, likely has one available for trade ahead of the deadline.

The SportsLine Projection Model has locked in its top anytime TD scorer picks for Minnesota vs. Los Angeles on Thursday Night Football