Starting in 2027, the Clemson Tigers will kick off a 12-game series against the Notre Dame Fighting Irish, set to last through the 2038 season. Athletic director Graham Neff cited the exciting games in the past,

Clemson football will face Notre Dame in a home-and-home series starting in 2027. It will mark Clemson's second home-and-home series with a non-ACC school.

Notre Dame and Clemson already know each other pretty well in football. That relationship will become even more familiar in the future after the two college football powers announced a 12-year home-and-home scheduling agreement that will pit them against each other annually from 2027 through 2038.