The synthesis and subsequent functionalisation of amides have emerged as pivotal areas in modern synthetic chemistry, enabling the direct conversion of these otherwise inert functional groups into ...

The authors’ approach is deceptively simple: take an aldehyde dehydrogenase enzyme, which naturally converts aldehydes to acids, and get it to react with an amine instead of water. But actually making ...

A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...

Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. Scientists have now introduced a new type of reaction for making amide ...

Amides are among the most ubiquitous functional groups in organic chemistry, forming the backbone of peptides and playing a vital role in pharmaceutical, synthetic and materials chemistry. Their ...

Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...