A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Two-step nanocage: Individual enzymes (orange and green) are first attached to half-cage structures. Half cages are then assembled into full cages, where reactants are brought into close proximity.

To be used industrially, enzymes usually need to undergo some surgery before they can become chemical workhorses. It may take a nip here, or a tuck there, to sculpt their active site into a shape that ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Researchers imagine autonomous nanosized devices sailing through the blood stream, detecting molecular signs of disease or delivering drugs. Such devices will need nanomotors that can drive and steer ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 15 (April 9, 2019), pp. 7298-7307 (10 pages) Thousands of biochemical reactions with characterized ...

Enzymes are biological molecules (typically proteins) that significantly speed up the rate of virtually all of the chemical reactions that take place within cells. They are vital for life and serve a ...