MIT engineers have developed a new way to amplify the T-cell response to mRNA vaccines—an advance that could lead to much ...

Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell ...

• This study aimed to investigate the immunophenotype of esophageal cancer (ESCA) by assessing the patient’s immune defenses or autoimmune function and to identify potential tumor antigens and ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...

Across the immunity cycle, NPs can co-deliver tumor antigens and adjuvants to DCs, enhance major histocompatibility complex class I (MHC-I)-mediated cross-presentation, and promote cytotoxic T ...

Artificial antigen-presenting cells (aAPCs) are engineered constructs designed to emulate the functions of professional antigen-presenting cells. By displaying tumour-associated peptide–MHC complexes ...

Researchers have reported two major immunology advances: Weill Cornell Medicine scientists found that activated T cells secrete DNA-filled vesicles that can enhance immune responses against tumors, ...

For years, one of the most powerful weapons against certain blood cancers, called CAR-T therapy, has required an elaborate process: Doctors extract a patient’s immune cells, ship them to a specialized ...

Scientists have uncovered an unexpected mechanism by which the gut’s immune system maintains balance, challenging ...

FDA authorization supports a mid-stage clinical evaluation of CK0802 in steroid-refractory GVHD, where steroid nonresponse is ...