Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Duchenne muscular dystrophy (DMD) is a severe X-linked myopathy characterised by progressive skeletal and cardiac muscle ...
A complex cellular process called autophagy is the topic of a major new textbook which encapsulates over 30 years of research in this growing field of study. A complex cellular process called ...
Findings underpin potential of Anavex’ lead candidate blarcamesine through its upstream mechanism of action and SIGMAR1-mediated autophagy restorationNEW YORK, March 20, 2026 (GLOBE NEWSWIRE) -- ...
Cells face constant threats from inside and out. Thus, they’ve evolved sophisticated stress response pathways such as the unfolded protein response (UPR), ...
Anavex Life Sciences Corp. AVXL on Friday announced that a new peer-reviewed study published by the University of California ...
A group of molecules found in trendy anti-aging treatments may actually feed cancer cells, a study has revealed. Polyamines are natural compounds present in all living cells that trigger autophagy, ...
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