In the realm of biomanufacturing, space-time yield (STY) is increasingly recognized as an essential metric for evaluating upstream process efficiency. STY facilitates the direct comparison of various ...

The antibiotic cefazolin is an essential drug according to the World Health Organization (WHO). It is usually produced via batch manufacturing, but this multistep process is time-consuming, wasteful ...

DIANT is a startup co-founded by Antonio Costa, Ph.D. and Diane Burgess, Ph.D. In 2020, DIANT licensed their core manufacturing technology from UConn and was granted a patent on the technology earlier ...

Continuous pharmaceutical manufacturing represents a significant shift from traditional batch processing, integrating continuous flow methods, advanced process analytical technology (PAT) and ...

In a recent article, a U.K. group outlined their vision for downstream process analytic technology (PAT) and quality by design (QbD) within the context of batch vs. continuous chromatography. The ...

The manufacture of medicines must draw on expertise from a wide range of disciplines, from the initial investigation and design of a new drug or therapeutic to wide-scale production and distribution, ...