Bone is continuously renewed through a process known as bone remodeling, in which osteoblasts (bone-forming cells) build new ...

"[...] our work suggests that increased mtROS or decreased Atg7-dependent autophagy in osteoblastic cells, as well as reduced osteocyte dendrite number – common ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

Researchers have shown that a naturally occurring peptide (small protein) holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct advantages over ...

Around 40% of adults worldwide are affected by osteopenia: a loss of bone mineral density. This condition is extremely common particularly in postmenopausal women and elderly adults. It’s estimated ...