Am J Health Syst Pharm. 2009;66(8):715-726. Mechanism of action of maraviroc. Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of ...
In the three and a half decades since HIV/AIDS was discovered, the deadly disease has killed 35 million people. While drugs now allow patients to live long lives with the virus, only one man, an ...
A total of seven individuals worldwide (two patients in Berlin and patients in London, Düsseldorf, New York, City of Hope and Geneva) are considered likely to have been cured or to be in long-term ...
At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...
A few decades ago, the idea of an HIV cure sounded unrealistic. Today, doctors describe a carefully documented case where the virus appears to be gone for good after a rare stem cell transplant. A ...
Some people infected with HIV are teeming with virus, but don’t get sick. Their resistive powers probably come from a mix of genetics and unique immune responses, according to a study of such rare ...
A 60-year-old man in Germany has become at least the seventh person with HIV to be announced free of the virus after receiving a stem-cell transplant. But the man, who has been virus-free for close to ...
A 60-year-old German man is likely the seventh person to be effectively cured from HIV after receiving a stem cell transplant, doctors announced on Thursday. The painful and risky procedure is for ...
Am J Health Syst Pharm. 2009;66(8):715-726. Since MOTIVATE 1 and MOTIVATE 2 used identical study designs and endpoints, the results of the two trials were pooled for further analysis. [29] The ...
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