Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked ...

Researchers have investigated the effect of increased cell temperature on the contractility of skeletal muscle and cardiac muscle by heating the muscle proteins using advanced microscopical techniques ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid say they have identified a key role for the MKK3/6–p38γ/δ signaling pathway in the development of cardiac ...

Hierarchical structure of muscle and activation of thin filaments. In both skeletal and cardiac muscles under a relaxed state, a low intracellular calcium ion concentration is maintained and the ...