The controlled activation of cell death pathways triggers an acute, transient inflammatory response that, combined with the efficient phagocytosis of dead cells, ultimately restores tissue homeostasis ...

The interplay between immune responses and cell death pathways is a central theme in immunology and pathology. Recent developments emphasize that these ...

An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes. Led by NYU Langone Health researchers, a new study in mice showed that a drug candidate prevented ...

(L) Corresponding author Thirumala-Devi Kanneganti, PhD, St. Jude Center of Excellence for Innate Immunity and Inflammation director and Department of Immunology vice chair and (R) and first author ...

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from the University of Milan highlights the beneficial effect of inhibiting the death ...

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn’s disease, ...

Every drop of blood in the human body traces back to a small reserve of stem cells buried inside bone marrow. These hematopoietic stem cells generate red blood cells, white blood cells and platelets ...

Accro Bioscience Inc. ("Accro Bioscience"), a clinical-stage biotechnology company pioneering the development of novel therapeutics that target molecular mechanisms of regulatory cell death for immune ...

Scientists have uncovered a surprising dark side to vitamin B2: it may help cancer cells stay alive. The vitamin supports a ...

Chemotherapy drugs that target a common mutation in colorectal cancer rapidly lose efficacy in patients, leading to relapse.

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway that leads to increased insulin production. The research is published in ...