Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...
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Jumping genes reshape cancer genomes through 3D chromatin interactions
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.
Cell-line development enhances biopharmaceutical production capacity and quality, but complex biologics like bsAbs and ADCs present new challenges.
SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.
Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...
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Mapping pre-myelinating oligodendrocytes: New mouse line links neuronal activity to cell survival
Nerve fibers in the brain and spinal cord are wrapped in an insulating sheath known as myelin. For a long time, this barrier, which is essentially the brain's white matter, was believed to serve the ...
Dlc1 deletion affects cardiac differentiation in mouse embryonic stem cells by activating the canonical Wnt pathway ...
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