A new strategy strengthens the bond between the T cell and a target tumor cell, improving the cytotoxic function of the T cell.

UCLA and Stanford Medicine researchers, in collaboration with scientists from the University of Utah and Columbia University, ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors. One in every three FDA-approved drugs targets a single ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...

Scientists have built functional cancer-fighting immune cells directly inside living animals, skipping the expensive and time ...

Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and bind to receptors on the surface of target cells, a molecular arms race that ...