There is growing enthusiasm in the pharmaceutical industry for whole-system functional assays that reveal the action of potential drugs on integrated systems such as intact cells in order to find ...

The 8-Bromo-cAMP sodium salt PKA activator, a synthetic analog of cAMP, is one of the most potent tools of investigating and playing with this pathway, which has become an essential part of ...

Using cutting-edge bioinformatics techniques for gene identification and sequencing, researchers are comprehensively mapping signaling pathway distributions in both normal and acne-affected skin. Acne ...

Cells live in a world of chaos, constantly buffeted by random molecular jolts that can derail even the most carefully tuned ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

A group of researchers has identified the cause of a 'short-circuit' in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases and could lead to development ...

A new study has found an answer for a long-lasting question in aging research - Is Alzheimer’s disease-dementia a form of accelerated aging or is there a different path that can lead us to healthier ...

Neurodegenerative disorders are pressing global health challenges that stem from progressive neuronal dysfunction and loss. While the central roles of ...

Research provides the first-ever high-resolution, cell-resolved map of the human scalp during early aging. In A Nutshell Hair ...