Chloride channels and antiport mechanisms are pivotal for maintaining cellular ion homeostasis and regulating physiological processes such as muscle contraction, epithelial fluid transport and ...

Calcium-activated chloride channels (CaCCs) play a pivotal role in a myriad of physiological processes. By responding to intracellular calcium concentration, these channels regulate epithelial ...

A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists have now analyzed the effect of a point mutation that was found in three unrelated ...

The field of neurotrauma and epilepsy research has increasingly highlighted the pivotal influence of ion channels in the transition from traumatic brain ...

A new study by University of Iowa researchers finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface. This function is exactly the ...