Study: Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity. Image Credit: Alex Mit / Shutterstock.com Ventral tegmental area dopamine ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

The ‘gray area’ of addiction.

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

While scientists really do seem to love getting rats loaded on cocaine, a new study of rodents getting high on the lab's supply reveals intriguing new insights into how individuals respond differently ...

Smoking instead of injecting drugs can reduce harm, but a new study shows opioid smokers are four times as likely to suffer severe burns.

We know that addicts lose control over their lives and that they would as soon give up breathing as stop using their preferred substance/s. Yet, the critical question of why one member of an ...