Proliferating cells, in particular tumor cells, express a dimeric isoenzyme of pyruvate kinase, termed Tumor M2 pyruvate kinase. In the last few years, much attention has been paid to this novel tumor ...

Colorectal cancer is among the most common malignant tumor types and the second leading cause of tumor-related deaths worldwide. Tumor necrosis factor α-induced protein 8-like protein 2 (TIPE2) is a ...

However, tumor marker tests aren’t the only tools they’ll use in cancer care. Other testing techniques will help provide a more comprehensive look at your type of cancer. Regular cells may produce ...

Tumor marker blood tests may help inform various aspects of cancer care, including diagnosis, staging, treatment planning, and outlook. However, they’re often not the only diagnostic tests used. If ...

A newly uncovered immune chain reaction in the gut may explain why people with inflammatory bowel disease face a much higher ...

Immune signaling in IBD triggers tumor-promoting neutrophils which is linked to an increased risk of colorectal cancer.

Colorectal cancer can be treated using immunotherapy approaches that use the immune cells to target cancer cells and induce the killing of those cancer cells. Some colorectal cancer types have been ...