Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are switched on.

Oxford and Cambridge researchers who produced the image map which uncovers the secrets of why humans get disease say it 'changes our understanding of how genes work’

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions in the ring are occupied by carbon atoms. (Image: Public ...

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that provides vital chemical units for the synthesis of DNA,

A better understanding of protein glycosylation offers insights into disease mechanisms and helps improve therapeutic medicines.