Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process rewards, regulate impulses and weigh consequences—not from genes that ...

What if a single choice could hijack your brain’s wiring, rewriting your behavior, judgment, and even your ability to survive? The human brain is an essential organ in the body, responsible for ...

Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

In addition to their weight loss benefits, GLP-1 RAs also act on neural circuits involved in appetite, impulse control, and ...

Hoebel and researchers in the department of psychology and the Princeton Neuroscience Institute have demonstrated patterns of craving and relapse, the third and final stage of addiction, that had ...

Laura holds a Master's in Experimental Neuroscience and a Bachelor's in Biology from Imperial College London. Her areas of expertise include health, medicine, psychology, and neuroscience. Laura holds ...

About 1 in 5 individuals develop a substance use disorder; more than 46 million people in the United States are affected at any given time. And yet, most people choose to use alcohol or other drugs ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

The psychedelic drug ibogaine is a Schedule I controlled substance, but Kentucky lawmakers are considering a bill researching ...

Dr. Harriet de Wit's groundbreaking 45-year journey bridges animal and human drug research, reshaping global understanding of consciousness CHICAGO, Illinois, USA, 26 August 2025 -- In a revealing ...