The selective estrogen receptor modulator tamoxifen is one of the most frequently prescribed anticancer therapies worldwide. It is highly efficacious in the adjuvant setting for early stage, estrogen ...

Endometrial and colorectal cancers are the most common cancers in Lynch syndrome. Consensus guidelines recommend annual endometrial biopsy (EMB) and regular colonoscopies. We assessed the feasibility ...

Endometrial build-up and cyclic changes are guided by ovarian hormonal signals. In a spontaneous cycle, the endometrium regenerates from the basal membrane after menstruation. This is primarily in ...

The endometrium is the layer of tissue lining the inside of the uterus – the reproductive organ in the pelvis where a baby develops. "The endometrium is a crucial part of the female reproductive ...

A study published this week suggests that epigenetic modification of the HAND2 gene plays a critical role in the development of endometrial cancer. HAND2 is active in the healthy endometrium (the ...

When classifying cellular uterine mesenchymal neoplasms, histological distinction of endometrial stromal from smooth muscle neoplasms can be difficult. The only widely established marker of ...