In a study published in Cell Research, researchers have identified a fibrous-layer resident subpopulation of P-SSCs labeled ...

Bone fractures usually heal efficiently, but in some patients this process fails, causing nonunion. A recent study identifies ...

image: Tppp3+ tendon sheath progenitors expand at the heterotopic ossification (HO) induction site after Achilles tendon injury. a Schematic representation of HO induction, including complete Achilles ...

Bone fractures usually heal efficiently, but in some patients this process fails, causing nonunion. A recent study identifies ...

Bone regeneration research has taken a significant leap forward with the discovery of a crucial mechanism that could transform treatments for bone disorders. Scientists have identified how Discoidin ...

A new small molecule could treat and prevent excess bone formation. Fibrodysplasia ossificans progressiva (FOP) is an extremely rare disease estimated to affect about one in 2 million people worldwide ...

"Historically viewed as mainly a “wear and tear” condition, new insights suggest that OA may be part of an evolutionary, age-related biological process rather than mainly driven by mechanical damage." ...

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from ...

Heterotopic ossification happens when bone grows outside of its normal location and into the surrounding soft tissues of your body. When this happens, the pieces of bone that develop are called ...

Bent bone dysplasia (BBD) is a perinatal-lethal skeletal disorder caused by pathogenic FGFR2 mutations that disrupt bone formation, leading to bent long bones, osteopenia, and craniosynostosis. Bent ...