Macrophages accumulate free cholesterol in advanced atherosclerotic lesions, resulting in macrophage apoptosis and progression of lesions 1,2,3,4,5,6,7,8. Previous studies with cultured macrophages ...
Endoplasmic reticulum (ER)-associated degradation (ERAD) is a secretory protein quality control process that results in the removal of aberrant proteins from the ER. ERAD substrates are selected by ...
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