Sugars known as glycans form dense envelopes around cells. But they’re often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are ...

A new paper in Nature Communications illuminates how a previously poorly understood enzyme works in the cell. Many diseases are tied to chronic cellular stress, and UMBC's Aaron T. Smith and ...

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases ...

Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name. Cell migration inducing and hyaluronan-binding protein (CEMIP) is associated with disorders ...

Enzymes are the molecular machines that power life; they build and break down molecules, copy DNA, digest food, and drive virtually every chemical reaction in our cells. For decades, scientists have ...

Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the production ...

Researchers have found a small molecule enzyme inhibitor capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases. Researchers at the University of ...

Neurodegenerative diseases like Alzheimer's disease or Parkinson's disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the ...

An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress ...

BUFFALO, N.Y. – Sugars known as glycans form dense envelopes around cells. But they’re often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to ...