Embryonic development is a meticulously orchestrated process in which spatial and temporal cues guide cell fate determination and tissue patterning. Central to this process is morphogen signalling – a ...

Paired box 6 (PAX6) is a member of the highly conserved paired box (PAX) transcription factors. Transcription factors regulate the activity of large numbers of genes involved in development. The PAX6 ...

Multicellularity is one of the most profound phenomena in biology, and relies on the ability of a single cell to reorganize itself into a complex organism. It underpins the diversity in the animal ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever experimenting ...