Spiroindolone-resistant P. falciparum isolates bearing mutations in PfATP4 can be selected in vitro, 8 and it will be essential to combine KAE609 with a reliably effective second drug to provide ...

Malaria, caused by Plasmodium falciparum, remains a major global health threat, claiming 600,000 lives annually, mostly young ...

WEHI researchers have visualized a key protein complex in malaria parasites for the first time, uncovering a new target for next-generation vaccines that could help stop the disease from spreading.

In a scientific first, researchers have decoded a naturally acquired antibody directly from the blood of a child exposed to ...

Hesperos, the human-on-a-chip company, models the full life cycle of a deadly malaria parasite by combining a human ...

A genomic study of malaria samples from Tanzania and Zanzibar found mutations connected to artemisinin partial resistance, ...

When you get bitten, up to 200 P. falciparum passengers enter your bloodstream, where they glide around looking for liver cells in which to hide, multiply and transform. Within a week, each of ...

We evaluated the efficacy and safety of KAF156 in a two-step process. First, 400 mg of KAF156 was given once daily for 3 days to patients with uncomplicated vivax malaria (cohort 1) or falciparum ...

The Scientist's content tagged with: Plasmodium Falciparum.From manipulating host molecules to concealing their presence in the host’s body, microbes employ a wide range of tactics to dodge immune ...

Why do you think this is the case? The P. falciparum RAP01 and RAP21 proteins that we studied belong to the "RNA-binding domain abundant in Apicomplexans" (RAP) protein family.