Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Here, we report that the protein accumulates in ...

Initially identified as a ‘simple’ glycolytic enzyme, glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is tightly regulated at both transcriptional and posttranslational levels and has numerous ...

Researchers characterized a new protein that affects how cells in the innate immune system function and protect humans against invading bacteria such as E. coli O157:H7. A Kansas State University-led ...

A novel study reveals that targeting a single protein’s aggregation can dramatically reduce brain injury after stroke, potentially transforming how acute ischemic strokes are treated. Study: ...