The brain may lose control over which genes get expressed as it ages.

Researchers have found that certain bacteria carry a naturally occurring system, built from repurposed CRISPR components, that switches genes on rather than cutting or silencing DNA. The discovery, ...

In their landmark 1961 paper on the lac operon, Nobel laureates François Jacob and Jacques Monod speculated that RNA might control gene activity in bacteria through base-pairing interactions. But once ...

Rutgers‑led study of 2.2 million people finds addiction risk is driven more by genes tied to impulse control and reward ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

In a recent study published in the journal Nature Biotechnology, researchers describe the pA regulator system based on a ribonucleic acid (RNA)-based switch to regulate mammalian gene expression by ...

An analysis of 2.2 million people reveals both shared and substance-specific genetic pathways for addiction risk, showing ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...