Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

An overview of where next-generation sequencing is used, from whole-genome variant discovery to clinical liquid biopsy and single-cell transcriptomics.

Researchers at University of Tsukuba have developed "tomoseqr"—a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free ...

Researchers have developed 'tomoseqr' -- a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free to use and has been ...

Researchers at the Yale School of Public Health have discovered the evolutionary rhythm of gene expression, showing that changes happen at strikingly varied rates. In the study, published in Molecular ...

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they ...