Gene-set analysis seeks to identify the biological mechanisms underlying groups of genes with shared functions. Large language models (LLMs) have shown promise in generating functional descriptions ...

We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

The authors define a gene module as a group of genes with similar expression patterns across different conditions and hence likely to be functionally related. Mishra and colleagues studied gene ...

Researchers developed theoretical foundations for methods that could identify the best way to aggregate genes into modules and efficiently learn the underlying cause-and-effect relationships among ...

A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has been completed and released on a new website. For the first ...

Thanks to increasingly efficient and affordable gene sequencing technologies, we can now chart our genetic blueprint in unprecedented detail. But what does each gene do? Of the roughly 20,000 genes ...