PURPOSE: To define prognostic factors for response and long-term outcome for a wide spectrum of osteosarcomas, extending well beyond those of the typical young patient with seemingly localized ...

Large-scale analysis of patient cohorts reveals a novel mechanism driving osteosarcoma, an aggressive paediatric bone cancer. The researchers show that this mechanism occurs in approximately 50% of ...

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 ...

The researchers analysed the largest available collection of whole-genome data from osteosarcoma patients and identified a new mutation mechanism called loss-translocation-amplification (LTA) ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...

A 52-year-old man had a radical right colectomy for a sarcoma of the cecal wall (high grade of malignancy, 10 cells/field). On a postoperative computerized tomography (CT) scan 2 months later, a 3-cm ...