Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...

Researchers have used a new human reference genome, which includes many duplicated and repeat sequences left out of the original human genome draft, to identify genes that make the human brain ...

A major medical milestone took place in May 2025, when doctors at the Children’s Hospital of Philadelphia used CRISPR-based gene editing to treat a child with a rare genetic disorder. Unlike earlier ...

A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has been completed and released on a new website. For the first ...

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- ...

Most research in human genetics has historically focused on people of European ancestries—a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.

Putting the uniquely human version of a certain gene into mice changed the way that those animals vocalized to each other, suggesting that this gene may play a role in speech and language. Mice make a ...

Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ancestry, according to a study published in Nature Communications. Researchers ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Scientists have identified hundreds of genes that may increase the risk of developing Alzheimer’s disease but the roles these genes play in the brain are poorly understood. This lack of understanding ...