Human neuroblastoma cell lines, particularly SH-SY5Y, have become central to studies of human neuronal differentiation owing to their reproducibility, ease of culture and capacity to adopt mature ...

A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides ...

For years, one of the simplest explanations for human intelligence was also one of the biggest: the human brain has an enormous number of neurons. It also has an even more enormous web of connections ...

What makes the human brain capable of language, imagination, mathematics and invention? For many years, the prevailing view ...

New, previously unpublished clinical data have been presented at ISSCR 2026 demonstrating that transplanted human neural ...

A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...

The brain's mechanisms for repairing injuries caused by trauma or degenerative diseases are not yet known in detail. Now, a study by the University of Barcelona describes a new strategy based on stem ...

A cluster of new studies has identified several previously overlooked biological routes through which Alzheimer’s disease ...

New research uncovers the impact of excess iron accumulation in neurons, causing vulnerability to stress and leading to ...

A team led by Jason Shepherd at the University of Utah has identified the protein responsible for loading toxic tau into tiny ...