An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways ...

Ulcerative colitis (UC) is a chronic inflammatory disease of the gastrointestinal tract, which is closely related to gut barrier dysfunction. Emerging evidence shows that interleukin-22 (IL-22) ...

Children with a variant in the SERPINE1 gene—which is found in 60% of the population—may be less responsive to mepolizumab, a ...

Diagnostic pathways are often inappropriate in paediatric inflammatory bowel disease, with many cases bypassing proper evaluation; severe intestinal symptoms are linked to appropriate pathways.

University of Washington researchers have used stem cell-derived kidney organoids to uncover inflammatory pathways that drive ...

Newswise — By identifying quercetin and caffeic acid as the most active compounds, the researchers demonstrated that these molecules significantly reduce inflammatory cytokine production in immune ...

Inflammation is part of your body’s natural healing process after infection or injury. But when inflammation persists for ...

Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that starts ...

Ovarian cancer remains one of the deadliest malignancies affecting women, largely because it is frequently diagnosed only ...

Inflammation associated with asthma and other allergic airway diseases can be significantly worsened by exposure to both house dust mite allergens and crystalline silica, according to a new study ...

The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients. New research led by ...