Super immunodeficient mouse models with knockout of murine Fc gamma receptors (FcγRs) have emerged as valuable tools in biomedical research for improving the accuracy of preclinical experimental ...

Progranulin is an obvious target for a frontotemporal dementia therapy, as up to 15 percent of cases arise from loss-of-function mutations in its gene, GRN. In a study published January 7 in Science ...