Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular ...

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases ...

Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease, affecting more than ...

Long recognized as the cell’s recycling depot, a new study has found lysosomes act as signaling hubs that coordinate metabolism and longevity by communicating signals across tissues. According to a ...

Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is ...

Scientists at Baylor College of Medicine, the Howard Hughes Medical Institute (HHMI) and collaborating institutions report in the journal Nature Cell Biology that lysosomes in roundworms produce ...

For the first time, the pathway through which cells repair damaged lysosomes has been observed and described. Lysosomes are the recycling center of a cell, where molecular waste is degraded into the ...

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical viral particles, colorized blue, contain cross-section through ...

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions ...

Cells have extensive sets of intracellular membranes, which together compose the endomembrane system. The endomembrane system was first discovered in the late 1800s when scientist Camillo Golgi ...

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...