This important study combines optogenetic manipulations and wide-field imaging to show that the retrosplenial cortex controls behavioral responses to whisker deflection in a context-dependent manner.

Harnessing the muscle of one of the world's fastest supercomputers, researchers have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever. This ...

Vision shapes behavior, and a new study by MIT neuroscientists finds behavior and internal states shape vision. The research, published in Neuron, finds in mice that, via specific circuits, the ...

Biophysically detailed simulation of the whole mouse cortex neuron by neuron, with sub-cellular resolution—that is, capturing ion flows and fluctuations of membrane voltage within many compartments ...

Creating a virtual brain may sound like a science-fiction nightmare, but for neuroscientists in Japan and at Seattle’s Allen Institute, it’s a big step toward a long-held dream. They say their ...

Orbitofrontal cortex (OFC) in green. Source: Paul Wicks/Wickemedia Commons In a groundbreaking discovery, neurocientists at the University of California, Berkeley, have captured brain images of active ...

Much as a pilot might practice maneuvers in a flight simulator, scientists might soon be able to perform experiments on a realistic simulation of the mouse brain. In a new study, Stanford Medicine ...

Acupuncture treatment on the DU channel has shown therapeutic effects for Alzheimer’s disease (AD), but the underlying mechanisms are not yet clear. The purpose of this study was to comprehensively ...