Skeletal and heart muscles contract and relax upon sliding of parallel filaments of the proteins myosin and actin. Nebulin, another long slender protein, which is present only in skeletal muscle, ...

Skeletal and heart muscles contract and relax upon sliding of parallel filaments of the proteins myosin and actin. Nebulin, another long slender protein, which is present only in skeletal muscle, ...

Nebulin is a giant modular sarcomeric protein that has been proposed to play critical roles in myofibrillogenesis, thin filament length regulation, and muscle contraction. To investigate the ...

Nemaline myopathy is a clinically and genetically heterogeneous muscle disorder. A common denominator for nemaline myopathy patients is pathological disorganization of the muscle Z discs and ...

Insulin-like growth factor 1 (IGF-1) induces skeletal muscle maturation and enlargement (hypertrophy). These responses require protein synthesis and myofibril formation (myofibrillogenesis). However, ...

Nebulin (pink) was identified by comparing cardiac and skeletal thin filament structures. Actin, nebulin, tropomyosin, myosin heavy chain, myosin essential light chain and myosin regulatory light ...

Nebulin Antibody (1F4) is available as the non-conjugated anti-Nebulin antibody. Caldesmon, filamin 1, nebulin and villin are differentially expressed and regulated actin binding proteins. Both ...

Scientists have obtained the first high-resolution 3D image of nebulin, a giant actin-binding protein that is an essential component of skeletal muscle. This discovery has brought to light the chance ...