Skeletal and heart muscles contract and relax upon sliding of parallel filaments of the proteins myosin and actin. Nebulin, another long slender protein, which is present only in skeletal muscle, ...
Skeletal and heart muscles contract and relax upon sliding of parallel filaments of the proteins myosin and actin. Nebulin, another long slender protein, which is present only in skeletal muscle, ...
Nebulin is a giant modular sarcomeric protein that has been proposed to play critical roles in myofibrillogenesis, thin filament length regulation, and muscle contraction. To investigate the ...
Nebulin (pink) was identified by comparing cardiac and skeletal thin filament structures. Actin, nebulin, tropomyosin, myosin heavy chain, myosin essential light chain and myosin regulatory light ...
This is a preview. Log in through your library . Abstract In many tissues, actin monomers polymerize into actin (thin) filaments of precise lengths. Although the exact mechanisms involved remain ...
SipA is a Salmonella protein delivered into host cells to promote efficient bacterial entry, which is essential for pathogenicity. SipA exerts its function by binding F-actin, resulting in the ...
The nemaline myopathies are muscle disorders characterised by muscle weakness and hypotonia, and histologically by the presence in the muscle fibres of threadlike nemaline bodies composed mainly of ...
Scientists have obtained the first high-resolution 3D image of nebulin, a giant actin-binding protein that is an essential component of skeletal muscle. This discovery has brought to light the chance ...
Heart and skeletal muscle owe their function as reliable biological machines to the extraordinary precision with which their smallest contractile structures, the sarcomeres, are assembled. Generating ...
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