This post was written by Adrien Fillon from the University of Aix-Marseille, France, who led a meta-analysis of the "exceptionality effect" discussed in this post. Gilad Feldman, the corresponding ...

Rare-variant association studies (RVAS) have made important contributions to human complex trait genetics. These studies rely on specialized statistical methods for analyzing rare-variant associations ...

There are many variations to Hans Christian Andersen’s classic literary folktale “The Emperor’s New Clothes,” but most have the same basic plot points: A vain emperor is duped by two con men into ...