New study identifies CAR3 as a key osteoblast protein promoting collagen mineralization, bone formation, and skeletal ...

Osteoporosis is a common disorder, especially in the elderly, characterized by bone loss and increased fracture risk. Treatments target abnormal osteoclast activity but face adherence issues. The ...

New study identifies CAR3 as a key osteoblast protein promoting collagen mineralization, bone formation, and skeletal ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers has now identified an enzyme that controls the activity of osteoblasts. An ...

Bone formation and maintenance depend upon the precise coordination of osteoblast differentiation, matrix deposition and the balanced activity of bone-resorbing osteoclasts. Osteoblasts originate from ...

New research uncovers how the Clec14a protein in capillary endothelial cells controls bone growth and maturation, revealing a key mechanism in skeletal development. Study: Type-H endothelial cell ...

Endothelial-to-Osteoblast Conversion (EC-to-OSB) regulates bone formation and homeostasis via the Kindlin-2/Piezo1/TGFβ/Runx2 axis. Reduced Kindlin-2 in endothelial ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling—a ...

A decade-long study of nearly 10,000 older women found tea drinkers had higher hip bone mineral density. The post A 10-Year ...

One of the best-documented pathophysiological changes associated with microgravity and the spaceflight environment is bone loss. The reduction in bone mass and its effect following reentry could ...

Wif1 overexpression accelerated osteogenic differentiation by activating genes related to late-stage osteogenic differentiation and mitophagy processes. Moreover administering Wif1-overexpressing ...