Bone is continuously renewed through a process known as bone remodeling, in which osteoblasts (bone-forming cells) build new ...

There is mounting evidence that osteoblasts are involved in the regulation of global energy metabolism. Although osteocalcin signalling remains important, the complexity of systemic energy storage and ...

Epigenetic alterations in peripheral blood cell DNA and implications for breast cancer detection, prognosis, and treatment. Background: Bisphosphonates (BPs) are widely used for the treatment in bone ...

Telomere lengths in the hTERT-negative presenescent osteoblasts decreased with advancing population doublings in a manner comparable to the shortening seen in mass cultures at equivalent population ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers has now identified an enzyme that controls the activity of osteoblasts. An ...

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...

Panel A shows osteoclasts and osteoblasts in normal bone (toluidine blue, ×100). The large osteoclast is actively resorbing bone. Osteoblasts are small, cuboid cells that actively lay down bone matrix ...

Vitamin K has long been linked to bone health, but its precise role remained unclear. A new study shows that vitamin ...

In the future, stem cells may be used to treat osteoporosis. However, while the results from animal studies are promising, data in humans is very limited. Osteoporosis is currently treated with ...

Estrogen plays a protective role in bone health. When estrogen levels decrease, such as after menopause, your risk of osteoporosis and bone loss rises. There are steps you can take to reduce your risk ...