Effective axon regeneration is critical for restoring nerve function in patients with axon injury-related neurological diseases, yet adult mammals show limited regenerative capacity in central axonal ...

The peripheral nervous system is a vast network of nerves that exists primarily outside of brain and spinal cord and connects to the far reaches of the body. The very expanse of peripheral nerves ...

This is a preview. Log in through your library . Abstract In an effort to determine whether the "growth state" and the "mature state" of a neuron are differentiated by different programs of gene ...

Scientists have developed a gene therapy that blocks axonal degeneration, preventing axon destruction in mice and suggesting a therapeutic strategy that could help prevent the loss of peripheral ...

Researchers at Case Western Reserve University have developed a computer modeling method to accurately predict how a peripheral nerve axon responds to electrical stimuli, slashing the complex work ...

There’s a new option to help patients with chronic pain. NeuraLace Medical has received FDA clearance for its Axon Therapy, a technology that non-invasively stimulates peripheral nerves and provides ...

In humans, axons of the peripheral nervous system (PNS) are capable of regeneration, whereas those of the central nervous system (CNS) are currently viewed as incapable of regeneration. This inability ...

Injured axons instruct Schwann cells to build specialized actin spheres to break down and remove axon fragments, thereby starting the regeneration process. Damaged peripheral nerves can regenerate ...

The NEUROFUSE Study is an ongoing 48-week Multicenter, Randomized, evaluator-blinded, Phase 2a study in upper extremity nerve transections comparing NTX-001 adjunctive to standard of care (SOC) to SOC ...

An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes. This, in turn, has led to an increase in peripheral neuropathy—nerve damage, ...