Natural products are a rich source of lead compounds for new drugs. The discovery of biological activities of natural products plays a vital part in drug development and therapeutic strategies. The ...

Phosphatidate phosphatase (PAP) enzymes play a pivotal role in lipid metabolism, acting as a control point that directs metabolic flux between membrane phospholipid synthesis and the production of ...

KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, has discovered how cancer cells can ...

Before the onset of cardiovascular disease symptoms, people often develop dyslipidemia, or abnormal levels of lipids in the blood. Recent studies suggest that microbes in the gut play an important ...

In a recent study published in Cell Host & Microbe, researchers highlighted the role of lipids, especially bacteria-derived lipids in the gut microbiome, in mammalian physiology in the context of ...

Uncontrolled accumulation of reactive oxygen species (ROS) and sustained inflammation make diabetic wounds difficult to treat with conventional wound healing approaches. To address the problem, ...

Dyslipidemia, an imbalance of lipids, often precedes cardiovascular disease, the leading cause of death worldwide. The gut microbiota may help regulate lipids in the blood, but the details aren’t ...