Learn how a new microscope revealed living Antarctic fish cells in detail and why their protein-folding challenges could ...

An error in protein conformation can lead to disease. What are the genetic and molecular causes for incorrectly formed proteins? molecules. In 1917 the German chemist ...

A comprehensive analysis of over 500,000 human protein variants reveals that 60% of disease-causing missense mutations reduce protein stability In a recent study published in Nature, researchers used ...

One of the great biological mysteries of the human body is how hundreds of complex, origami-like proteins, many of which are crucial for normal body function, come to assume their final, correct shape ...

WEST LAFAYETTE, Ind. — The shared culprit in a slew of diseases — cancers, neurodegenerative diseases, diabetes — is molecules our cells have made incorrectly. Think of them as proteins gone wrong.

A University of Mississippi professor and his team have developed a technology that may one day lead to the early diagnosis of juvenile diabetes and CTE caused by traumatic brain injuries. The ...

Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new in vitro and ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

New research from David Westaway, director of the Center for Prions and Protein Folding Diseases at the University of Alberta, and Jiri Safar, co-director of the National Prion Disease Pathology ...

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...