Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...

The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for this important class of drug targets.

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...