Nature

‘Recirculating cardiac delivery’ method of gene delivery should be called ‘non-recirculating’ method

I am writing to you regarding a paper entitled ‘Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals’, which was ...
Nature

Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals

Despite pharmacologic advances in the treatment of heart failure (HF), mortality and morbidity remain unacceptably high. Moreover, for patients with end-stage HF therapeutic options are limited to ...