Steviol glycosides, natural sweeteners extracted from Stevia rebaudiana, are widely used as sucrose substitutes due to their high sweetness and low caloric value. Among them, Rebaudioside M (Reb M) is ...

Figure 1: Pyridine-containing drugs, pyridyne isomers and previous examples of pyridynes. Prior efforts to modulate regioselectivities of 3,4-pyridynes using substituent effects were met with ...