If your New Year resolution has been to lose weight and eat healthy, here is some good news – dark chocolate and red wine may actually help you achieve your goal. These two food items belong to the ...

Sirtuins are a family of NAD⁺-dependent deacetylases and ADP-ribosyltransferases that regulate cellular metabolism, stress responses and genomic stability. In the central nervous system, these enzymes ...

Sirtuin proteins are emerging as central regulators of oocyte competence and ovarian ageing, acting through their NAD⁺-dependent deacetylase activities to coordinate genome stability, mitochondrial ...

Key molecular regulators: Sirtuins are NAD+-dependent enzymes that link energy metabolism to gene regulation, stress responses, and mitochondrial health. Impact on aging: They preserve genomic ...