Symptoms of hereditary spastic paraparesis, including weakness of the legs, are due to deterioration of nerves in the spinal cord that control the leg muscles. The process of nerve deterioration ...

Hereditary spastic paraplegia (HSP), also known as familial spastic paraparesis, is a term used for a group of inherited diseases that affect the upper motor neurons traveling from the brain through ...

Spastic paraplegia type 47 (SPG47) is a rare congenital and neurological disorder characterized by dysfunction of the long axons in the corticospinal tract neurons that lead to progressive limb ...

Spastic diplegia cerebral palsy (SDCP) is a form of cerebral palsy that causes muscle stiffness and spasms in a person’s legs and, sometimes, arms. This is due to damage to the motor cortex of the ...

Quadriparesis is a condition in which you have muscle weakness in all four of your limbs (both legs and both arms). Also called tetraparesis, this weakness and diminished mobility can be temporary or ...

Intrathecal baclofen (ITB) therapy is an established treatment for severe refractory spasticity. Although a positive ITB ...

Spasticity may be a term that’s new to you, but it’s a condition that affects more than 12 million people around the world. [8] It’s a complicated condition, but simply put, it’s extreme muscle ...

Spasticity causes chronic muscle tightness and stiffness that keep muscles contracted, reducing mobility and affecting both large movements like walking and fine motor skills like eating or writing.