Researchers of the Melnick Lab, led by Prof. Ari Melnick, medicine, recently published a study identifying a key mutation that disrupts the B-cell natural selection process during immune response, ...

A new study by researchers at the University of Wisconsin–Madison provides the first empirical evidence connecting the chromosomal location of genes to natural selection, indicating the arrangement of ...

The key to understanding how the most aggressive lymphomas arise and resist current therapies may lie in mutations that disrupt a critical natural selection process among antibody-producing B cells, ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...